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Alanine repeats influence protein localization in splicing speckles and paraspeckles
Mammalian splicing regulatory protein RNA-binding motif protein 4 (RBM4) has an alanine repeat-containing C-terminal domain (CAD) that confers both nuclear- and splicing speckle-targeting activities. Alanine-repeat expansion has pathological potential. Here we show that the alanine-repeat tracts inf...
Autores principales: | Chang, Shuo-Hsiu, Chang, Wei-Lun, Lu, Chia-Chen, Tarn, Woan-Yuh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267627/ https://www.ncbi.nlm.nih.gov/pubmed/25414336 http://dx.doi.org/10.1093/nar/gku1159 |
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