The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells

The H19 lncRNA has been implicated in development and growth control and is associated with human genetic disorders and cancer. Acting as a molecular sponge, H19 inhibits microRNA (miRNA) let-7. Here we report that H19 is significantly decreased in muscle of human subjects with type-2 diabetes and i...

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Detalles Bibliográficos
Autores principales: Gao, Yuan, Wu, Fuju, Zhou, Jichun, Yan, Lei, Jurczak, Michael J., Lee, Hui-Young, Yang, Lihua, Mueller, Martin, Zhou, Xiao-Bo, Dandolo, Luisa, Szendroedi, Julia, Roden, Michael, Flannery, Clare, Taylor, Hugh, Carmichael, Gordon G., Shulman, Gerald I., Huang, Yingqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267628/
https://www.ncbi.nlm.nih.gov/pubmed/25399420
http://dx.doi.org/10.1093/nar/gku1160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267628/
https://www.ncbi.nlm.nih.gov/pubmed/25399420
http://dx.doi.org/10.1093/nar/gku1160

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