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The TCF C-clamp DNA binding domain expands the Wnt transcriptome via alternative target recognition

LEF/TCFs direct the final step in Wnt/β-catenin signalling by recruiting β-catenin to genes for activation of transcription. Ancient, non-vertebrate TCFs contain two DNA binding domains, a High Mobility Group box for recognition of the Wnt Response Element (WRE; 5′-CTTTGWWS-3′) and the C-clamp domai...

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Detalles Bibliográficos
Autores principales:	Hoverter, Nate P., Zeller, Michael D., McQuade, Miriam M., Garibaldi, Angela, Busch, Anke, Selwan, Elizabeth M., Hertel, Klemens J., Baldi, Pierre, Waterman, Marian L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267635/ https://www.ncbi.nlm.nih.gov/pubmed/25414359 http://dx.doi.org/10.1093/nar/gku1186

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