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In silico prediction of splice-altering single nucleotide variants in the human genome
In silico tools have been developed to predict variants that may have an impact on pre-mRNA splicing. The major limitation of the application of these tools to basic research and clinical practice is the difficulty in interpreting the output. Most tools only predict potential splice sites given a DN...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267638/ https://www.ncbi.nlm.nih.gov/pubmed/25416802 http://dx.doi.org/10.1093/nar/gku1206 |