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Prediction of DNA binding motifs from 3D models of transcription factors; identifying TLX3 regulated genes

Proper cell functioning depends on the precise spatio-temporal expression of its genetic material. Gene expression is controlled to a great extent by sequence-specific transcription factors (TFs). Our current knowledge on where and how TFs bind and associate to regulate gene expression is incomplete...

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Detalles Bibliográficos
Autores principales: Pujato, Mario, Kieken, Fabien, Skiles, Amanda A., Tapinos, Nikos, Fiser, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267649/
https://www.ncbi.nlm.nih.gov/pubmed/25428367
http://dx.doi.org/10.1093/nar/gku1228