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Brr2p carboxy-terminal Sec63 domain modulates Prp16 splicing RNA helicase

RNA helicases are essential for virtually all cellular processes, however, their regulation is poorly understood. The activities of eight RNA helicases are required for pre-mRNA splicing. Amongst these, Brr2p is unusual in having two helicase modules, of which only the amino-terminal helicase domain...

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Detalles Bibliográficos
Autores principales: Cordin, Olivier, Hahn, Daniela, Alexander, Ross, Gautam, Amit, Saveanu, Cosmin, Barrass, J. David, Beggs, Jean D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267655/
https://www.ncbi.nlm.nih.gov/pubmed/25428373
http://dx.doi.org/10.1093/nar/gku1238