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AGO2 and SETDB1 cooperate in promoter-targeted transcriptional silencing of the androgen receptor gene

In mammals, RNA interference is primarily a post-transcriptional mechanism. Evidence has accumulated for additional role in transcriptional gene silencing (TGS) but the question for a good paradigm for small interfering antigene RNA (agRNA)-induced chromatin modification remains unanswered. Here, we...

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Detalles Bibliográficos
Autores principales: Cho, Sunwha, Park, Jung Sun, Kang, Yong-Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267665/
https://www.ncbi.nlm.nih.gov/pubmed/25183519
http://dx.doi.org/10.1093/nar/gku788