Diverse cell stresses induce unique patterns of tRNA up- and down-regulation: tRNA-seq for quantifying changes in tRNA copy number

Emerging evidence points to roles for tRNA modifications and tRNA abundance in cellular stress responses. While isolated instances of stress-induced tRNA degradation have been reported, we sought to assess the effects of stress on tRNA levels at a systems level. To this end, we developed a next-gene...

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Detalles Bibliográficos
Autores principales: Pang, Yan Ling Joy, Abo, Ryan, Levine, Stuart S., Dedon, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267671/
https://www.ncbi.nlm.nih.gov/pubmed/25348403
http://dx.doi.org/10.1093/nar/gku945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267671/
https://www.ncbi.nlm.nih.gov/pubmed/25348403
http://dx.doi.org/10.1093/nar/gku945

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