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Profiling small RNA reveals multimodal substructural signals in a Boltzmann ensemble
As the biomedical impact of small RNAs grows, so does the need to understand competing structural alternatives for regions of functional interest. Suboptimal structure analysis provides significantly more RNA base pairing information than a single minimum free energy prediction. Yet computational en...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267672/ https://www.ncbi.nlm.nih.gov/pubmed/25392423 http://dx.doi.org/10.1093/nar/gku959 |