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Profiling small RNA reveals multimodal substructural signals in a Boltzmann ensemble

As the biomedical impact of small RNAs grows, so does the need to understand competing structural alternatives for regions of functional interest. Suboptimal structure analysis provides significantly more RNA base pairing information than a single minimum free energy prediction. Yet computational en...

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Detalles Bibliográficos
Autores principales: Rogers, Emily, Heitsch, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267672/
https://www.ncbi.nlm.nih.gov/pubmed/25392423
http://dx.doi.org/10.1093/nar/gku959

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