A bottom-up characterization of transfer functions for synthetic biology designs: lessons from enzymology

Within the field of synthetic biology, a rational design of genetic parts should include a causal understanding of their input-output responses—the so-called transfer function—and how to tune them. However, a commonly adopted strategy is to fit data to Hill-shaped curves without considering the unde...

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Detalles Bibliográficos
Autores principales: Carbonell-Ballestero, Max, Duran-Nebreda, Salva, Montañez, Raúl, Solé, Ricard, Macía, Javier, Rodríguez-Caso, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267673/
https://www.ncbi.nlm.nih.gov/pubmed/25404136
http://dx.doi.org/10.1093/nar/gku964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267673/
https://www.ncbi.nlm.nih.gov/pubmed/25404136
http://dx.doi.org/10.1093/nar/gku964

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