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A bottom-up characterization of transfer functions for synthetic biology designs: lessons from enzymology
Within the field of synthetic biology, a rational design of genetic parts should include a causal understanding of their input-output responses—the so-called transfer function—and how to tune them. However, a commonly adopted strategy is to fit data to Hill-shaped curves without considering the unde...
Autores principales: | Carbonell-Ballestero, Max, Duran-Nebreda, Salva, Montañez, Raúl, Solé, Ricard, Macía, Javier, Rodríguez-Caso, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267673/ https://www.ncbi.nlm.nih.gov/pubmed/25404136 http://dx.doi.org/10.1093/nar/gku964 |
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