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A Novel Mouse Model of Advanced Diabetic Kidney Disease

Currently available rodent models exhibit characteristics of early diabetic nephropathy (DN) such as hyperfiltration, mesangial expansion, and albuminuria yet features of late DN (hypertension, GFR decline, tubulointerstitial fibrosis) are absent or require a significant time investment for full phe...

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Detalles Bibliográficos
Autores principales: Thibodeau, Jean-Francois, Holterman, Chet E., Burger, Dylan, Read, Naomi C., Reudelhuber, Timothy L., Kennedy, Christopher R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267730/
https://www.ncbi.nlm.nih.gov/pubmed/25514595
http://dx.doi.org/10.1371/journal.pone.0113459