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Arsenite-Induced Pseudo-Hypoxia Results in Loss of Anchorage-Dependent Growth in BEAS-2B Pulmonary Epithelial Cells

Epidemiology studies have established a strong link between lung cancer and arsenic exposure. Currently, the role of disturbed cellular energy metabolism in carcinogenesis is a focus of scientific interest. Hypoxia inducible factor-1 alpha (HIF-1A) is a key regulator of energy metabolism, and it has...

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Detalles Bibliográficos
Autores principales: Zhao, Fei, Malm, Scott W., Hinchman, Alyssa N., Li, Hui, Beeks, Connor G., Klimecki, Walter T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267735/
https://www.ncbi.nlm.nih.gov/pubmed/25513814
http://dx.doi.org/10.1371/journal.pone.0114549