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Unprecedented Therapeutic Potential with a Combination of A(2A)/NR2B Receptor Antagonists as Observed in the 6-OHDA Lesioned Rat Model of Parkinson's Disease

In Parkinson's disease, the long-term use of dopamine replacing agents is associated with the development of motor complications; therefore, there is a need for non-dopaminergic drugs. This study evaluated the potential therapeutic impact of six different NR2B and A(2A) receptor antagonists giv...

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Detalles Bibliográficos
Autores principales: Michel, Anne, Downey, Patrick, Nicolas, Jean-Marie, Scheller, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267740/
https://www.ncbi.nlm.nih.gov/pubmed/25513815
http://dx.doi.org/10.1371/journal.pone.0114086