Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application

Through epithelial-mesenchymal transition (EMT), cancer cells acquire enhanced ability of migration and invasion, stem cell like characteristics and therapeutic resistance. Notch signaling regulates cell-cell connection, cell polarity and motility during organ development. Recent studies demonstrate...

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Detalles Bibliográficos
Autores principales: Yuan, Xun, Wu, Hua, Han, Na, Xu, Hanxiao, Chu, Qian, Yu, Shiying, Chen, Yuan, Wu, Kongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267749/
https://www.ncbi.nlm.nih.gov/pubmed/25477004
http://dx.doi.org/10.1186/s13045-014-0087-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267749/
https://www.ncbi.nlm.nih.gov/pubmed/25477004
http://dx.doi.org/10.1186/s13045-014-0087-z

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