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Serotonin/Dopamine Interactions in a Hyperactive Mouse: Reduced Serotonin Receptor 1B Activity Reverses Effects of Dopamine Transporter Knockout

Knockout (KO) mice that lack the dopamine transporter (SL6A3; DAT) display increased locomotion that can be attenuated, under some circumstances, by administration of drugs that normally produce psychostimulant-like effects, such as amphetamine and methylphenidate. These results have led to suggesti...

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Detalles Bibliográficos
Autores principales: Hall, Frank Scott, Sora, Ichiro, Hen, René, Uhl, George R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267809/
https://www.ncbi.nlm.nih.gov/pubmed/25514162
http://dx.doi.org/10.1371/journal.pone.0115009