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The Role of Transcription in the Activation of a Drosophila Amplification Origin

The mechanisms that underlie metazoan DNA replication initiation, especially the connection between transcription and replication origin activation, are not well understood. To probe the role of transcription in origin activation, we exploited a specific replication origin in Drosophila melanogaster...

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Detalles Bibliográficos
Autores principales: Hua, Brian L., Li, Sharon, Orr-Weaver, Terry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267935/
https://www.ncbi.nlm.nih.gov/pubmed/25320071
http://dx.doi.org/10.1534/g3.114.014050