Cargando…

A Versatile Two-Step CRISPR- and RMCE-Based Strategy for Efficient Genome Engineering in Drosophila

The development of clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated (Cas) technologies promises a quantum leap in genome engineering of model organisms. However, CRISPR-mediated gene targeting reports in Drosophila melanogaster are still restricted to a few gene...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xu, Koolhaas, Wouter H., Schnorrer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267936/
https://www.ncbi.nlm.nih.gov/pubmed/25324299
http://dx.doi.org/10.1534/g3.114.013979