Characterization of the Mutagenic Spectrum of 4-Nitroquinoline 1-Oxide (4-NQO) in Aspergillus nidulans by Whole Genome Sequencing

4-Nitroquinoline 1-oxide (4-NQO) is a highly carcinogenic chemical that induces mutations in bacteria, fungi, and animals through the formation of bulky purine adducts. 4-NQO has been used as a mutagen for genetic screens and in both the study of DNA damage and DNA repair. In the model eukaryote Asp...

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Detalles Bibliográficos
Autores principales: Downes, Damien J., Chonofsky, Mark, Tan, Kaeling, Pfannenstiel, Brandon T., Reck-Peterson, Samara L., Todd, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267943/
https://www.ncbi.nlm.nih.gov/pubmed/25352541
http://dx.doi.org/10.1534/g3.114.014712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267943/
https://www.ncbi.nlm.nih.gov/pubmed/25352541
http://dx.doi.org/10.1534/g3.114.014712

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