Loss of signaling via Gα13 in germinal center B cell-derived lymphoma

Germinal center (GC) B cell-like diffuse large B cell lymphoma (GCB-DLBCL) is a common malignancy yet the signaling pathways deregulated and the factors leading to its systemic dissemination are poorly defined(1,2). Work in mice showed that sphingosine-1-phosphate receptor-2 (S1PR2), a Gα12 and Gα13...

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Detalles Bibliográficos
Autores principales: Muppidi, Jagan R., Schmitz, Roland, Green, Jesse A., Xiao, Wenming, Larsen, Adrien B., Braun, Sterling E., An, Jinping, Xu, Ying, Rosenwald, Andreas, Ott, German, Gascoyne, Randy D., Rimsza, Lisa M., Campo, Elias, Jaffe, Elaine S., Delabie, Jan, Smeland, Erlend B., Braziel, Rita M., Tubbs, Raymond R., Cook, J. R., Weisenburger, Dennis D., Chan, Wing C., Vaidehi, Nagarajan, Staudt, Louis M., Cyster, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267955/
https://www.ncbi.nlm.nih.gov/pubmed/25274307
http://dx.doi.org/10.1038/nature13765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267955/
https://www.ncbi.nlm.nih.gov/pubmed/25274307
http://dx.doi.org/10.1038/nature13765

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