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Natalizumab-related anaphylactoid reactions in MS patients are associated with HLA class II alleles

OBJECTIVES: We aimed to investigate potential associations between human leukocyte antigen (HLA) class I and class II alleles and the development of anaphylactic/anaphylactoid reactions in patients with multiple sclerosis (MS) treated with natalizumab. METHODS: HLA class I and II genotyping was perf...

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Detalles Bibliográficos
Autores principales: de la Hera, Belén, Urcelay, Elena, Brassat, David, Chan, Andrew, Vidal-Jordana, Angela, Salmen, Anke, Villar, Luisa Maria, Álvarez-Cermeño, José Carlos, Izquierdo, Guillermo, Fernández, Oscar, Oliver, Begoña, Saiz, Albert, Ara, Jose Ramón, Vigo, Ana G., Arroyo, Rafael, Meca, Virginia, Malhotra, Sunny, Fissolo, Nicolás, Horga, Alejandro, Montalban, Xavier, Comabella, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268037/
https://www.ncbi.nlm.nih.gov/pubmed/25520955
http://dx.doi.org/10.1212/NXI.0000000000000047