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An Intergenic Regulatory Region Mediates Drosophila Myc -Induced Apoptosis and Blocks Tissue Hyperplasia

Induction of cell autonomous apoptosis following oncogene-induced overproliferation is a major tumor-suppressive mechanism in vertebrates. However the detailed mechanism mediating this process remains enigmatic. In this study we demonstrate that dMyc-induced cell-autonomous apoptosis in the fruit fl...

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Detalles Bibliográficos
Autores principales: Zhang, Can, Tintó, Sergio Casas, Li, Guangyao, Lin, Nianwei, Chung, Michelle, Moreno, Eduardo, Moberg, Kenneth H., Zhou, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268096/
https://www.ncbi.nlm.nih.gov/pubmed/24931167
http://dx.doi.org/10.1038/onc.2014.160