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Genomic profiling of human Leishmania braziliensis lesions identifies transcriptional modules associated with cutaneous immunopathology

The host immune response plays a critical role not only in protection from human leishmaniasis, but also in promoting disease severity. Although candidate gene approaches in mouse models of leishmaniasis have been extremely informative, a global understanding of the immune pathways active in lesions...

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Detalles Bibliográficos
Autores principales: Novais, Fernanda O., Carvalho, Lucas P., Passos, Sara, Roos, David S., Carvalho, Edgar M., Scott, Phillip, Beiting, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268311/
https://www.ncbi.nlm.nih.gov/pubmed/25036052
http://dx.doi.org/10.1038/jid.2014.305