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Genomic profiling of human Leishmania braziliensis lesions identifies transcriptional modules associated with cutaneous immunopathology
The host immune response plays a critical role not only in protection from human leishmaniasis, but also in promoting disease severity. Although candidate gene approaches in mouse models of leishmaniasis have been extremely informative, a global understanding of the immune pathways active in lesions...
Autores principales: | Novais, Fernanda O., Carvalho, Lucas P., Passos, Sara, Roos, David S., Carvalho, Edgar M., Scott, Phillip, Beiting, Daniel P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268311/ https://www.ncbi.nlm.nih.gov/pubmed/25036052 http://dx.doi.org/10.1038/jid.2014.305 |
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