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An evolutionary arms race between KRAB zinc finger genes 91/93 and SVA/L1 retrotransposons
Throughout evolution, primate genomes have been modified by waves of retrotransposon insertions(1,2,3). For each wave, the host eventually finds a way to repress retrotransposon transcription and prevent further insertions. In mouse embryonic stem cells (mESCs), transcriptional silencing of retrotra...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268317/ https://www.ncbi.nlm.nih.gov/pubmed/25274305 http://dx.doi.org/10.1038/nature13760 |