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FPR1 interacts with CFH, HTRA1 and smoking in exudative age-related macular degeneration and polypoidal choroidal vasculopathy

PURPOSE: To determine the genetic association of an inflammation-related gene, formyl peptide receptor 1 (FPR1), in exudative age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). METHODS: The coding region of FPR1 gene was sequenced in 554 unrelated Chinese individuals...

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Detalles Bibliográficos
Autores principales: Liang, X Y, Chen, L J, Ng, T K, Tuo, J, Gao, J-L, Tam, P O S, Lai, T Y Y, Chan, C-C, Pang, C P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268466/
https://www.ncbi.nlm.nih.gov/pubmed/25277308
http://dx.doi.org/10.1038/eye.2014.226