TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis

Although there has been much success in identifying genetic variants associated with common diseases using genome-wide association studies (GWAS)(1), it has been difficult to demonstrate which variants are causal and what role they play in disease. Moreover, the modest contribution these variants ma...

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Detalles Bibliográficos
Autores principales: Gregory, Adam P., Dendrou, Calliope A., Attfield, Kathrine E., Haghikia, Aiden, Xifara, Dionysia K., Butter, Falk, Poschmann, Gereon, Kaur, Gurman, Lambert, Lydia, Leach, Oliver A., Prömel, Simone, Punwani, Divya, Felce, James H., Davis, Simon J., Gold, Ralf, Nielsen, Finn C., Siegel, Richard M., Mann, Matthias, Bell, John I., McVean, Gil, Fugger, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268493/
https://www.ncbi.nlm.nih.gov/pubmed/22801493
http://dx.doi.org/10.1038/nature11307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268493/
https://www.ncbi.nlm.nih.gov/pubmed/22801493
http://dx.doi.org/10.1038/nature11307

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