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WP1066 Sensitizes Oral Squamous Cell Carcinoma Cells to Cisplatin by Targeting STAT3/miR-21 axis

Accumulating evidence reveals that activation of STAT3 and miR-21 contributes to chemoresistance in multiple tumors. We examined the expression of STAT3 and miR-21 in 43 oral squamous cell carcinoma (OSCC) tumors and classified them into cisplatin sensitive or resistant group. Tca8113 and Tca8113/DD...

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Detalles Bibliográficos
Autores principales: Zhou, Xuan, Ren, Yu, Liu, Aiqin, Jin, Rui, Jiang, Qingping, Huang, Yuanyuan, Kong, Lingping, Wang, Xudong, Zhang, Lun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268632/
https://www.ncbi.nlm.nih.gov/pubmed/25514838
http://dx.doi.org/10.1038/srep07461