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Cell type-specific delivery of short interfering RNAs by dye-functionalised theranostic nanoparticles

Efficient delivery of short interfering RNAs reflects a prerequisite for the development of RNA interference therapeutics. Here, we describe highly specific nanoparticles, based on near infrared fluorescent polymethine dye-derived targeting moieties coupled to biodegradable polymers. The fluorescent...

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Detalles Bibliográficos
Autores principales: Press, Adrian T., Traeger, Anja, Pietsch, Christian, Mosig, Alexander, Wagner, Michael, Clemens, Mark G., Jbeily, Nayla, Koch, Nicole, Gottschaldt, Michael, Bézière, Nicolas, Ermolayev, Volodymyr, Ntziachristos, Vasilis, Popp, Jürgen, Kessels, Michael M., Qualmann, Britta, Schubert, Ulrich S., Bauer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268698/
https://www.ncbi.nlm.nih.gov/pubmed/25470305
http://dx.doi.org/10.1038/ncomms6565