Oligodendrocyte ablation triggers central pain independently of innate or adaptive immune responses in mice

Mechanisms underlying central neuropathic pain are poorly understood. Although glial dysfunction has been functionally linked with neuropathic pain, very little is known about modulation of pain by oligodendrocytes. Here we report that genetic ablation of oligodendrocytes rapidly triggers a pattern...

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Detalles Bibliográficos
Autores principales: Gritsch, Simon, Lu, Jianning, Thilemann, Sebastian, Wörtge, Simone, Möbius, Wiebke, Bruttger, Julia, Karram, Khalad, Ruhwedel, Torben, Blanfeld, Michaela, Vardeh, Daniel, Waisman, Ari, Nave, Klaus-Armin, Kuner, Rohini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268702/
https://www.ncbi.nlm.nih.gov/pubmed/25434649
http://dx.doi.org/10.1038/ncomms6472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268702/
https://www.ncbi.nlm.nih.gov/pubmed/25434649
http://dx.doi.org/10.1038/ncomms6472

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