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Oligodendrocyte ablation triggers central pain independently of innate or adaptive immune responses in mice
Mechanisms underlying central neuropathic pain are poorly understood. Although glial dysfunction has been functionally linked with neuropathic pain, very little is known about modulation of pain by oligodendrocytes. Here we report that genetic ablation of oligodendrocytes rapidly triggers a pattern...
Autores principales: | Gritsch, Simon, Lu, Jianning, Thilemann, Sebastian, Wörtge, Simone, Möbius, Wiebke, Bruttger, Julia, Karram, Khalad, Ruhwedel, Torben, Blanfeld, Michaela, Vardeh, Daniel, Waisman, Ari, Nave, Klaus-Armin, Kuner, Rohini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268702/ https://www.ncbi.nlm.nih.gov/pubmed/25434649 http://dx.doi.org/10.1038/ncomms6472 |
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