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Osthole improves synaptic plasticity in the hippocampus and cognitive function of Alzheimer's disease rats via regulating glutamate☆

Osthole, an effective monomer in Chinese medicinal herbs, can cross the blood-brain barrier and protect against brain injury, with few toxic effects. In this study, a rat model of Alzheimer's disease was established after intracerebroventricular injection of β-amyloid peptide (25–35). Subsequen...

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Detalles Bibliográficos
Autores principales: Dong, Xiaohua, Zhang, Danshen, Zhang, Li, Li, Wei, Meng, Xianyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268736/
https://www.ncbi.nlm.nih.gov/pubmed/25538756
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.30.001