A novel nanobiotherapeutic poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] with no cardiac toxicity for the resuscitation of a rat model with 90 minutes of sustained severe hemorrhagic shock with loss of 2/3 blood volume

We crosslink hemoglobin (Hb), superoxide dismutase (SOD), catalase (CAT), and carbonic anhydrase (CA) to form a soluble polyHb-SOD-CAT-CA nanobiotechnological complex. The obtained product is a soluble complex with three enhanced red blood cell (RBC) functions and without blood group antigens. In th...

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Detalles Bibliográficos
Autores principales: Bian, Yuzhu, Chang, Thomas Ming Swi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268802/
https://www.ncbi.nlm.nih.gov/pubmed/25297052
http://dx.doi.org/10.3109/21691401.2014.964554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268802/
https://www.ncbi.nlm.nih.gov/pubmed/25297052
http://dx.doi.org/10.3109/21691401.2014.964554

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