Cargando…
TNFα signalling primes chromatin for NF-κB binding and induces rapid and widespread nucleosome repositioning
BACKGROUND: The rearrangement of nucleosomes along the DNA fiber profoundly affects gene expression, but little is known about how signalling reshapes the chromatin landscape, in three-dimensional space and over time, to allow establishment of new transcriptional programs. RESULTS: Using micrococcal...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268828/ https://www.ncbi.nlm.nih.gov/pubmed/25608606 http://dx.doi.org/10.1186/s13059-014-0536-6 |