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Simultaneous downregulation of KLF5 and Fli1 is a key feature underlying systemic sclerosis

Systemic sclerosis (SSc) is manifested by fibrosis, vasculopathy and immune dysregulation. So far, a unifying hypothesis underpinning these pathological events remains unknown. Given that SSc is a multifactorial disease caused by both genetic and environmental factors, we focus on the two transcript...

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Detalles Bibliográficos
Autores principales: Noda, Shinji, Asano, Yoshihide, Nishimura, Satoshi, Taniguchi, Takashi, Fujiu, Katsuhito, Manabe, Ichiro, Nakamura, Kouki, Yamashita, Takashi, Saigusa, Ryosuke, Akamata, Kaname, Takahashi, Takehiro, Ichimura, Yohei, Toyama, Tetsuo, Tsuruta, Daisuke, Trojanowska, Maria, Nagai, Ryozo, Sato, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268882/
https://www.ncbi.nlm.nih.gov/pubmed/25504335
http://dx.doi.org/10.1038/ncomms6797