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Homocysteine downregulates gene expression of heme oxygenase-1 in hepatocytes
BACKGROUND: Hyperhomocysteinemia (HHcy) is an independent risk factor for liver diseases, such as fatty liver and hepatic fibrosis. However, the mechanisms underlying this pro-oxidative effect of homocysteine (Hcy) in hepatocytes remain largely unknown. Thus, we investigated the effect of Hcy on the...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268895/ https://www.ncbi.nlm.nih.gov/pubmed/25520741 http://dx.doi.org/10.1186/1743-7075-11-55 |