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Homocysteine downregulates gene expression of heme oxygenase-1 in hepatocytes

BACKGROUND: Hyperhomocysteinemia (HHcy) is an independent risk factor for liver diseases, such as fatty liver and hepatic fibrosis. However, the mechanisms underlying this pro-oxidative effect of homocysteine (Hcy) in hepatocytes remain largely unknown. Thus, we investigated the effect of Hcy on the...

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Detalles Bibliográficos
Autores principales:	Luo, Xiaoqin, Xiao, Lei, Yang, Haixia, Zhang, Ruijuan, Jiang, Manli, Ni, Jiahua, Lei, Ting, Wang, Nanping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268895/ https://www.ncbi.nlm.nih.gov/pubmed/25520741 http://dx.doi.org/10.1186/1743-7075-11-55

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