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Masking as an effective quality control method for next-generation sequencing data analysis

BACKGROUND: Next generation sequencing produces base calls with low quality scores that can affect the accuracy of identifying simple nucleotide variation calls, including single nucleotide polymorphisms and small insertions and deletions. Here we compare the effectiveness of two data preprocessing...

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Detalles Bibliográficos
Autores principales: Yun, Sajung, Yun, Sijung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268903/
https://www.ncbi.nlm.nih.gov/pubmed/25494997
http://dx.doi.org/10.1186/s12859-014-0382-2