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Masking as an effective quality control method for next-generation sequencing data analysis
BACKGROUND: Next generation sequencing produces base calls with low quality scores that can affect the accuracy of identifying simple nucleotide variation calls, including single nucleotide polymorphisms and small insertions and deletions. Here we compare the effectiveness of two data preprocessing...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268903/ https://www.ncbi.nlm.nih.gov/pubmed/25494997 http://dx.doi.org/10.1186/s12859-014-0382-2 |