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Preparation and characterization of self-assembled nanoparticles based on low-molecular-weight heparin and stearylamine conjugates for controlled delivery of docetaxel

Low-molecular-weight heparin (LMWH)–stearylamine (SA) conjugates (LHSA)-based self-assembled nanoparticles were prepared for intravenous delivery of docetaxel (DCT). 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide were used as coupling agents for synthesis of LHSA conjugates....

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Detalles Bibliográficos
Autores principales: Kim, Dong-Hwan, Termsarasab, Ubonvan, Cho, Hyun-Jong, Yoon, In-Soo, Lee, Jae-Young, Moon, Hyun Tae, Kim, Dae-Duk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268911/
https://www.ncbi.nlm.nih.gov/pubmed/25525355
http://dx.doi.org/10.2147/IJN.S74353