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Pathway activity inference for multiclass disease classification through a mathematical programming optimisation framework
BACKGROUND: Applying machine learning methods on microarray gene expression profiles for disease classification problems is a popular method to derive biomarkers, i.e. sets of genes that can predict disease state or outcome. Traditional approaches where expression of genes were treated independently...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269079/ https://www.ncbi.nlm.nih.gov/pubmed/25475756 http://dx.doi.org/10.1186/s12859-014-0390-2 |