Single-base resolution analysis of active DNA demethylation using methylase-assisted bisulfite sequencing

Active DNA demethylation in mammals involves TET-mediated iterative oxidation of 5-methylcytosine (5mC)/5-hydroxymethylcytosine (5hmC) and subsequent excision repair of highly oxidized cytosine bases 5-formylcytosine (5fC)/5-carboxylcytosine (5caC) by Thymine DNA glycosylase (TDG). However, quantita...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Wu, Xiaoji, Shen, Li, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269366/
https://www.ncbi.nlm.nih.gov/pubmed/25362244
http://dx.doi.org/10.1038/nbt.3073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269366/
https://www.ncbi.nlm.nih.gov/pubmed/25362244
http://dx.doi.org/10.1038/nbt.3073

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