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Pax6- and Six3-Mediated Induction of Lens Cell Fate in Mouse and Human ES Cells
Embryonic stem (ES) cells provide a potentially useful in vitro model for the study of in vivo tissue differentiation. We used mouse and human ES cells to investigate whether the lens regulatory genes Pax6 and Six3 could induce lens cell fate in vitro. To help assess the onset of lens differentiatio...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269389/ https://www.ncbi.nlm.nih.gov/pubmed/25517354 http://dx.doi.org/10.1371/journal.pone.0115106 |