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Pax6- and Six3-Mediated Induction of Lens Cell Fate in Mouse and Human ES Cells

Embryonic stem (ES) cells provide a potentially useful in vitro model for the study of in vivo tissue differentiation. We used mouse and human ES cells to investigate whether the lens regulatory genes Pax6 and Six3 could induce lens cell fate in vitro. To help assess the onset of lens differentiatio...

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Detalles Bibliográficos
Autores principales: Anchan, Raymond M., Lachke, Salil A., Gerami-Naini, Behzad, Lindsey, Jennifer, Ng, Nicholas, Naber, Catherine, Nickerson, Michael, Cavallesco, Resy, Rowan, Sheldon, Eaton, Jennifer L., Xi, Qiongchao, Maas, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269389/
https://www.ncbi.nlm.nih.gov/pubmed/25517354
http://dx.doi.org/10.1371/journal.pone.0115106