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Stubborn Contaminants: Influence of Detergents on the Purity of the Multidrug ABC Transporter BmrA

Despite the growing interest in membrane proteins, their crystallization remains a major challenge. In the course of a crystallographic study on the multidrug ATP-binding cassette transporter BmrA, mass spectral analyses on samples purified with six selected detergents revealed unexpected protein co...

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Detalles Bibliográficos
Autores principales: Wiseman, Benjamin, Kilburg, Arnaud, Chaptal, Vincent, Reyes-Mejia, Gina Catalina, Sarwan, Jonathan, Falson, Pierre, Jault, Jean-Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269414/
https://www.ncbi.nlm.nih.gov/pubmed/25517996
http://dx.doi.org/10.1371/journal.pone.0114864