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BMP signaling modulation attenuates cerebral arteriovenous malformation formation in a vertebrate model

Cerebral arteriovenous malformations (AVMs) are vascular anomalies that carry a high risk of stroke and death. To test potential AVM therapies, a reverse genetics approach was used to model AVMs in zebrafish. Antisense morpholino oligonucleotides were used to knockdown activin receptor-like kinase I...

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Detalles Bibliográficos
Autor principal: Walcott, Brian P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269730/
https://www.ncbi.nlm.nih.gov/pubmed/25052553
http://dx.doi.org/10.1038/jcbfm.2014.134