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BMP signaling modulation attenuates cerebral arteriovenous malformation formation in a vertebrate model
Cerebral arteriovenous malformations (AVMs) are vascular anomalies that carry a high risk of stroke and death. To test potential AVM therapies, a reverse genetics approach was used to model AVMs in zebrafish. Antisense morpholino oligonucleotides were used to knockdown activin receptor-like kinase I...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269730/ https://www.ncbi.nlm.nih.gov/pubmed/25052553 http://dx.doi.org/10.1038/jcbfm.2014.134 |