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Nonlinear Compliance Modulates Dynamic Bronchoconstriction in a Multiscale Airway Model

The role of breathing and deep inspirations (DI) in modulating airway hyperresponsiveness remains poorly understood. In particular, DIs are potent bronchodilators of constricted airways in nonasthmatic subjects but not in asthmatic subjects. Additionally, length fluctuations (mimicking DIs) have bee...

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Detalles Bibliográficos
Autores principales: Hiorns, Jonathan E., Jensen, Oliver E., Brook, Bindi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269780/
https://www.ncbi.nlm.nih.gov/pubmed/25517167
http://dx.doi.org/10.1016/j.bpj.2014.10.067