The Effect of a Connexin43-Based Peptide on the Healing of Chronic Venous Leg Ulcers: A Multicenter, Randomized Trial

The gap junction protein, connexin43 (Cx43), has critical roles in the inflammatory, edematous, and fibrotic processes following dermal injury and during wound healing, and is abnormally upregulated at the epidermal wound margins of venous leg ulcers (VLUs). Targeting Cx43 with ACT1, a peptide mimet...

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Detalles Bibliográficos
Autores principales: Ghatnekar, Gautam S, Grek, Christina L, Armstrong, David G, Desai, Sanjay C, Gourdie, Robert G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269806/
https://www.ncbi.nlm.nih.gov/pubmed/25072595
http://dx.doi.org/10.1038/jid.2014.318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269806/
https://www.ncbi.nlm.nih.gov/pubmed/25072595
http://dx.doi.org/10.1038/jid.2014.318

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